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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCI
All Species:
10.3
Human Site:
T187
Identified Species:
16.19
UniProt:
P41743
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41743
NP_002731.4
596
68262
T187
K
K
C
H
K
L
V
T
I
E
C
G
R
H
S
Chimpanzee
Pan troglodytes
XP_001148501
597
67369
D190
S
H
C
I
K
H
L
D
S
V
M
P
S
Q
E
Rhesus Macaque
Macaca mulatta
XP_001089400
597
68263
T188
K
K
C
H
K
L
V
T
I
E
C
G
R
H
S
Dog
Lupus familis
XP_535855
696
78257
T287
K
K
C
H
K
L
V
T
I
E
C
G
R
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62074
595
68185
V186
H
K
K
C
H
K
L
V
T
I
E
C
G
R
H
Rat
Rattus norvegicus
P09217
592
67715
P177
K
R
C
H
V
L
V
P
L
T
C
R
R
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506164
360
41199
Chicken
Gallus gallus
XP_417561
606
69931
P191
K
R
C
H
I
L
V
P
L
T
C
K
R
H
M
Frog
Xenopus laevis
NP_001084068
588
67442
V179
H
K
K
C
H
K
L
V
T
I
E
C
G
R
H
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
V179
H
K
K
C
H
K
L
V
T
V
E
C
G
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
N226
P
R
R
S
K
Y
L
N
Q
Q
G
G
E
D
N
Honey Bee
Apis mellifera
XP_397273
590
68031
R174
K
K
C
H
K
V
V
R
K
P
C
L
S
V
Q
Nematode Worm
Caenorhab. elegans
Q19266
597
68017
Q179
H
V
R
T
H
C
G
Q
A
L
Q
G
P
N
I
Sea Urchin
Strong. purpuratus
XP_780275
524
59689
R154
P
R
H
R
R
K
N
R
D
S
T
A
S
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T596
G
M
R
T
Q
K
K
T
H
K
D
K
A
S
S
Conservation
Percent
Protein Identity:
100
66.6
96.8
84.3
N.A.
98.3
72.3
N.A.
59.9
71.4
89.7
88.7
N.A.
36.4
67.9
58.1
63.5
Protein Similarity:
100
78.5
97.4
84.9
N.A.
98.8
83.5
N.A.
60.4
83
94.4
92.9
N.A.
54
78.1
74.1
72.4
P-Site Identity:
100
13.3
100
100
N.A.
6.6
53.3
N.A.
0
53.3
6.6
6.6
N.A.
13.3
46.6
6.6
0
P-Site Similarity:
100
20
100
100
N.A.
13.3
66.6
N.A.
0
66.6
13.3
13.3
N.A.
40
53.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
0
7
7
0
0
% A
% Cys:
0
0
47
20
0
7
0
0
0
0
40
20
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
7
0
7
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
20
20
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
7
0
0
0
7
34
20
0
0
% G
% His:
27
7
7
40
27
7
0
0
7
0
0
0
0
34
14
% H
% Ile:
0
0
0
7
7
0
0
0
20
14
0
0
0
0
7
% I
% Lys:
40
47
20
0
40
34
7
0
7
7
0
14
0
0
0
% K
% Leu:
0
0
0
0
0
34
34
0
14
7
0
7
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
14
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
0
0
0
7
7
% N
% Pro:
14
0
0
0
0
0
0
14
0
7
0
7
7
0
0
% P
% Gln:
0
0
0
0
7
0
0
7
7
7
7
0
0
7
14
% Q
% Arg:
0
27
20
7
7
0
0
14
0
0
0
7
34
20
0
% R
% Ser:
7
0
0
7
0
0
0
0
7
7
0
0
20
14
27
% S
% Thr:
0
0
0
14
0
0
0
27
20
14
7
0
0
0
7
% T
% Val:
0
7
0
0
7
7
40
20
0
14
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _